Diuretic Action of Ethacrynic Acid in Congestive Heart Failure
نویسندگان
چکیده
منابع مشابه
Ethacrynic Acid: Effectiveness and Mode of Diuretic Action in Man.
ETHACRYNIC ACID is an unsaturated ketone derivative of phenoxyacetic acid* chemically different from other known diuretic agents.' Compounds of this general class have a significant ability to bind sulfhydryl groups in vitro. Ethacrynic acid was shown by Baer and associates2 to be highly effective as a diuretic in the dog, but not in the rat. A preliminary report from this laboratory indicated ...
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ETHACRYNIC ACID is an unsaturated ketone derivative of phenoxyacetic acid* chemically different from other known diuretic agents.' Compounds of this general class have a significant ability to bind sulfhydryl groups in vitro. Ethacrynic acid was shown by Baer and associates2 to be highly effective as a diuretic in the dog, but not in the rat. A preliminary report from this laboratory indicated ...
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Diuretic drugs are used almost universally in patients with congestive heart failure, most frequently the potent loop diuretics. Despite their unproven effect on survival, their indisputable efficacy in relieving congestive symptoms makes them first line therapy for most patients. In the treatment of more advanced stages of heart failure diuretics may fail to control salt and water retention de...
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ژورنال
عنوان ژورنال: BMJ
سال: 1963
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5366.1169